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is the drug of choice for amebiases, vaginal trichomonasis and trichlomonadic urethritis in men, lambliosis, amebic dysentery, and anaerobic infections caused by microorganisms that are sensitive to the drug. Synonyms of this drug are flagyl, protostat, trichopol, and vagimid. is a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria. The first use of was to suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antiobiotic is that affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori, which is resistant to .
is a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria. The first use of was to suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antiobiotic is that affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori, which is resistant to .
